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Goldstein, A.L., et al
The effects of L-carnitine supplementation on inflammation, oxidative stress, and clinical outcomes in critically ill patients with sepsis: a randomized, double-blind, controlled trial
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However, reduction of HOMA-IR between groups was not significantly different (LC vs
Although -oxidation is impaired in the setting of VPA toxicity, this metabolite has a prolonged elimination half-life and could be responsible for the prolonged coma that is sometimes observed despite the normalization in plasma VPA concentrations [17, 18]
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